ea0090p77 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023
Tandl Veronika
, Schweighofer Natascha
, Trummer Olivia
, Haudum Christoph W.
, Lind Alice F.
, Kolesnik Ewald
, Mursic Ines
, Scherr Daniel
, Zirlik Andreas
, Pieber Thomas R.
, Verheyen Nicolas D.
, Obermayer-Pietsch Barbara
Sarcopenia is characterized by progressive loss of both mass and function of skeletal muscle when ageing. It poses a serious issue for healthcare systems, as it is associated with increased risk of falls, osteoporosis, and mortality. To date, no ideal serum biomarkers for the diagnosis of this complex condition have been identified. Matrix-GLA-protein (MGP), primarily known as a vitamin K dependent calcification inhibitor, is present and active in bone, muscle, and adipose tis...